在这项研究中，我们提出了一种基于聚类的方法在时间序列数据上，以在大流行早期捕获Covid-19传播模式。我们根据不同地理位置的不同国家的Covid-19早期和柱阶段分析了传播动力学。此外，我们调查监禁政策及其对蔓延的影响。我们发现相同监禁政策的实施表现出不同国家的不同结果。具体而言，由于遵守社会疏远措施，锁定在密集的地区变得不那么有效。在一些国家缺乏测试，联系跟踪和社会意识，迫使人们从自隔离和维持社会距离。具有不健康的生活条件的大型劳营营也有助于根据异国劳动的国家高社区传输。在政府政策和假新闻中的不信任煽动于发达国家和发达国家的传播。大型社交聚会在几乎到处造成快速爆发时发挥着至关重要的作用。虽然一些国家能够通过实施严格和广泛采用的监禁政策来遏制传播，但其他一些其他国家在社会疏远措施和严格的测试能力的帮助下载有传播。在大流行开始的早期和快速的反应是包含传播所必需的，但它并不总是足够的。

Compliance in actuation has been exploited to generate highly dynamic maneuvers such as throwing that take advantage of the potential energy stored in joint springs. However, the energy storage and release could not be well-timed yet. On the contrary, for multi-link systems, the natural system dynamics might even work against the actual goal. With the introduction of variable stiffness actuators, this problem has been partially addressed. With a suitable optimal control strategy, the approximate decoupling of the motor from the link can be achieved to maximize the energy transfer into the distal link prior to launch. However, such continuous stiffness variation is complex and typically leads to oscillatory swing-up motions instead of clear launch sequences. To circumvent this issue, we investigate decoupling for speed maximization with a dedicated novel actuator concept denoted Bi-Stiffness Actuation. With this, it is possible to fully decouple the link from the joint mechanism by a switch-and-hold clutch and simultaneously keep the elastic energy stored. We show that with this novel paradigm, it is not only possible to reach the same optimal performance as with power-equivalent variable stiffness actuation, but even directly control the energy transfer timing. This is a major step forward compared to previous optimal control approaches, which rely on optimizing the full time-series control input.

Deformable image registration is a key task in medical image analysis. The Brain Tumor Sequence Registration challenge (BraTS-Reg) aims at establishing correspondences between pre-operative and follow-up scans of the same patient diagnosed with an adult brain diffuse high-grade glioma and intends to address the challenging task of registering longitudinal data with major tissue appearance changes. In this work, we proposed a two-stage cascaded network based on the Inception and TransMorph models. The dataset for each patient was comprised of a native pre-contrast (T1), a contrast-enhanced T1-weighted (T1-CE), a T2-weighted (T2), and a Fluid Attenuated Inversion Recovery (FLAIR). The Inception model was used to fuse the 4 image modalities together and extract the most relevant information. Then, a variant of the TransMorph architecture was adapted to generate the displacement fields. The Loss function was composed of a standard image similarity measure, a diffusion regularizer, and an edge-map similarity measure added to overcome intensity dependence and reinforce correct boundary deformation. We observed that the addition of the Inception module substantially increased the performance of the network. Additionally, performing an initial affine registration before training the model showed improved accuracy in the landmark error measurements between pre and post-operative MRIs. We observed that our best model composed of the Inception and TransMorph architectures while using an initially affine registered dataset had the best performance with a median absolute error of 2.91 (initial error = 7.8). We achieved 6th place at the time of model submission in the final testing phase of the BraTS-Reg challenge.

In this paper, we consider incorporating data associated with the sun's north and south polar field strengths to improve solar flare prediction performance using machine learning models. When used to supplement local data from active regions on the photospheric magnetic field of the sun, the polar field data provides global information to the predictor. While such global features have been previously proposed for predicting the next solar cycle's intensity, in this paper we propose using them to help classify individual solar flares. We conduct experiments using HMI data employing four different machine learning algorithms that can exploit polar field information. Additionally, we propose a novel probabilistic mixture of experts model that can simply and effectively incorporate polar field data and provide on-par prediction performance with state-of-the-art solar flare prediction algorithms such as the Recurrent Neural Network (RNN). Our experimental results indicate the usefulness of the polar field data for solar flare prediction, which can improve Heidke Skill Score (HSS2) by as much as 10.1%.

Video summarization attracts attention for efficient video representation, retrieval, and browsing to ease volume and traffic surge problems. Although video summarization mostly uses the visual channel for compaction, the benefits of audio-visual modeling appeared in recent literature. The information coming from the audio channel can be a result of audio-visual correlation in the video content. In this study, we propose a new audio-visual video summarization framework integrating four ways of audio-visual information fusion with GRU-based and attention-based networks. Furthermore, we investigate a new explainability methodology using audio-visual canonical correlation analysis (CCA) to better understand and explain the role of audio in the video summarization task. Experimental evaluations on the TVSum dataset attain F1 score and Kendall-tau score improvements for the audio-visual video summarization. Furthermore, splitting video content on TVSum and COGNIMUSE datasets based on audio-visual CCA as positively and negatively correlated videos yields a strong performance improvement over the positively correlated videos for audio-only and audio-visual video summarization.

We present the development of a semi-supervised regression method using variational autoencoders (VAE), which is customized for use in soft sensing applications. We motivate the use of semi-supervised learning considering the fact that process quality variables are not collected at the same frequency as other process variables leading to many unlabelled records in operational datasets. These unlabelled records are not possible to use for training quality variable predictions based on supervised learning methods. Use of VAEs for unsupervised learning is well established and recently they were used for regression applications based on variational inference procedures. We extend this approach of supervised VAEs for regression (SVAER) to make it learn from unlabelled data leading to semi-supervised VAEs for regression (SSVAER), then we make further modifications to their architecture using additional regularization components to make SSVAER well suited for learning from both labelled and unlabelled process data. The probabilistic regressor resulting from the variational approach makes it possible to estimate the variance of the predictions simultaneously, which provides an uncertainty quantification along with the generated predictions. We provide an extensive comparative study of SSVAER with other publicly available semi-supervised and supervised learning methods on two benchmark problems using fixed-size datasets, where we vary the percentage of labelled data available for training. In these experiments, SSVAER achieves the lowest test errors in 11 of the 20 studied cases, compared to other methods where the second best gets 4 lowest test errors out of the 20.

We consider the problem of decision-making under uncertainty in an environment with safety constraints. Many business and industrial applications rely on real-time optimization with changing inputs to improve key performance indicators. In the case of unknown environmental characteristics, real-time optimization becomes challenging, particularly for the satisfaction of safety constraints. We propose the ARTEO algorithm, where we cast multi-armed bandits as a mathematical programming problem subject to safety constraints and learn the environmental characteristics through changes in optimization inputs and through exploration. We quantify the uncertainty in unknown characteristics by using Gaussian processes and incorporate it into the utility function as a contribution which drives exploration. We adaptively control the size of this contribution using a heuristic in accordance with the requirements of the environment. We guarantee the safety of our algorithm with a high probability through confidence bounds constructed under the regularity assumptions of Gaussian processes. Compared to existing safe-learning approaches, our algorithm does not require an exclusive exploration phase and follows the optimization goals even in the explored points, which makes it suitable for safety-critical systems. We demonstrate the safety and efficiency of our approach with two experiments: an industrial process and an online bid optimization benchmark problem.

A new development in NLP is the construction of hyperbolic word embeddings. As opposed to their Euclidean counterparts, hyperbolic embeddings are represented not by vectors, but by points in hyperbolic space. This makes the most common basic scheme for constructing document representations, namely the averaging of word vectors, meaningless in the hyperbolic setting. We reinterpret the vector mean as the centroid of the points represented by the vectors, and investigate various hyperbolic centroid schemes and their effectiveness at text classification.

Early evaluation of patients who require special care and who have high death-expectancy in COVID-19, and the effective determination of relevant biomarkers on large sample-groups are important to reduce mortality. This study aimed to reveal the routine blood-value predictors of COVID-19 mortality and to determine the lethal-risk levels of these predictors during the disease process. The dataset of the study consists of 38 routine blood-values of 2597 patients who died (n = 233) and those who recovered (n = 2364) from COVID-19 in August-December, 2021. In this study, the histogram-based gradient-boosting (HGB) model was the most successful machine-learning classifier in detecting living and deceased COVID-19 patients (with squared F1 metrics F1^2 = 1). The most efficient binary combinations with procalcitonin were obtained with D-dimer, ESR, D-Bil and ferritin. The HGB model operated with these feature pairs correctly detected almost all of the patients who survived and those who died (precision > 0.98, recall > 0.98, F1^2 > 0.98). Furthermore, in the HGB model operated with a single feature, the most efficient features were procalcitonin (F1^2 = 0.96) and ferritin (F1^2 = 0.91). In addition, according to the two-threshold approach, ferritin values between 376.2 mkg/L and 396.0 mkg/L (F1^2 = 0.91) and pro-calcitonin values between 0.2 mkg/L and 5.2 mkg/L (F1^2 = 0.95) were found to be fatal risk levels for COVID-19. Considering all the results, we suggest that many features combined with these features, especially procalcitonin and ferritin, operated with the HGB model, can be used to achieve very successful results in the classification of those who live, and those who die from COVID-19. Moreover, we strongly recommend that clinicians consider the critical levels we have found for procalcitonin and ferritin properties, to reduce the lethality of the COVID-19 disease.

While the Turkish language is listed among low-resource languages, literature on Turkish automatic speech recognition (ASR) is relatively old. In this report, we present our findings on Turkish ASR with speech representation learning using HUBERT. We investigate pre-training HUBERT for Turkish with large-scale data curated from online resources. We pre-train our model using 6,500 hours of speech data from YouTube. The results show that the models are not ready for commercial use since they are not robust against disturbances that typically occur in real-world settings such as variations in accents, slang, background noise and interference. We analyze typical errors and the limitations of the models for use in commercial settings.